Sunday, October 29, 2006

Waste DNA possible cause for arthritis

link
Fascinating hypothesis...our immune system also uses DNA as indicators of infection by microbes.. and DNA is quite universal so it might not be surprising that this creates problems...if someone shows that the 'garbage collectors' fail in function with age then perhaps it explains why arthritis appears in the elderly
"Like most of the molecular cogs that keep the human body running smoothly, DNA eventually outlives its usefulness and must be discarded. Red blood cells have no need for DNA and eject it once they become mature, and dying cells disintegrate, releasing DNA into the body. Special immune cells called macrophages function like garbage collectors, picking up this waste DNA and breaking it down."

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